SG Weightloss Weightloss Treatment

Is Wegovy Better Than Ozempic for Weight Loss?

Understanding Wegovy and Ozempic

Weight loss medications have become increasingly popular among individuals struggling with obesity and weight-related health conditions. Two of the most discussed options are Wegovy and Ozempic. Although both medications contain semaglutide, they are approved for different purposes and prescribed at different doses. This often leads patients to ask whether Wegovy is actually better than Ozempic for weight loss. Understanding how each treatment works can help you make a more informed decision with your healthcare provider.

What Is Wegovy?

Wegovy is a prescription medication containing semaglutide that is approved for chronic weight management in eligible adults. It helps regulate appetite, reduce food cravings, and increase feelings of fullness after meals.

What Is Ozempic?

Ozempic is also a semaglutide injection, but it was originally developed to improve blood sugar control in adults with type 2 diabetes. Many patients prescribed Ozempic also experience significant weight reduction during treatment.

Are Wegovy and Ozempic the Same Medication?

Both medications contain semaglutide and belong to a class of drugs called GLP-1 receptor agonists. However, they differ in approved indications, dosing schedules, and maximum maintenance doses.

How Do GLP-1 Medications Support Weight Loss?

GLP-1 receptor agonists mimic a naturally occurring hormone that helps regulate appetite and blood sugar levels. These medications slow stomach emptying, increase satiety, and reduce hunger signals sent to the brain. As a result, many patients consume fewer calories and gradually lose weight over time.

Wegovy vs Ozempic: What's the Difference?

While Wegovy and Ozempic share the same active ingredient, several important differences influence treatment outcomes.

Approved Uses and Indications

Wegovy is approved for weight management in adults with obesity or those who are overweight with weight-related medical conditions.

Ozempic is approved for type 2 diabetes management and cardiovascular risk reduction in certain patients with diabetes.

Active Ingredient Comparison

Both products contain Semaglutide. The primary difference lies in dosing strategies rather than the active ingredient itself.

Available Dosages and Strengths

Wegovy reaches a maintenance dose of 2.4 mg weekly. Ozempic typically reaches a maximum maintenance dose of 2 mg weekly, depending on clinical needs. This higher dose is one reason Wegovy may deliver greater weight loss results in some individuals.

Eligibility Requirements

Healthcare professionals consider body mass index, medical history, existing health conditions, and treatment goals before recommending either medication.

Is Wegovy Better Than Ozempic for Weight Loss?

For pure weight loss outcomes, current evidence generally favors Wegovy.

Weight Loss Results From Clinical Studies

The STEP 1 trial, published in The New England Journal of Medicine, found that participants receiving semaglutide 2.4 mg achieved an average weight reduction of approximately 14.9% over 68 weeks when combined with lifestyle interventions. In comparison, studies involving Ozempic have demonstrated meaningful weight loss, but average reductions are generally lower due to the lower maintenance dose.

Why Wegovy May Produce Greater Weight Loss

The higher semaglutide dose used in Wegovy provides stronger appetite suppression for many patients. This can contribute to greater calorie reduction and improved long-term weight management.

How Much Weight Can You Expect to Lose?

Individual results vary based on starting weight, diet quality, physical activity levels, medication adherence, and underlying health conditions. Some patients experience modest reductions, while others achieve substantial weight loss over the course of treatment.

According to the Singapore National Population Health Survey, approximately 1 in 10 Singaporean adults live with obesity, and more than 4 in 10 are overweight using Asian BMI thresholds. For Singaporeans managing weight-related conditions such as type 2 diabetes, hypertension, or high cholesterol, semaglutide treatments like Wegovy and Ozempic may offer clinically meaningful benefits beyond weight reduction alone.

How Long Does It Take to See Results?

Many patients begin noticing changes within the first few months. Meaningful results often become more apparent after dose escalation and consistent treatment adherence.

Side Effects: Wegovy vs Ozempic

Because both medications contain semaglutide, they share many similar side effects.


Common Side Effects

Common side effects include:

  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation
  • Abdominal discomfort
  • Reduced appetite

These symptoms often improve as the body adjusts to treatment.


Serious Safety Considerations

Although uncommon, serious side effects may include pancreatitis, gallbladder disease, severe allergic reactions, and kidney complications.

Patients should seek immediate medical attention if concerning symptoms develop.


Which Medication Causes More Side Effects?

Since Wegovy uses a higher maintenance dose, some patients may experience gastrointestinal symptoms more frequently during dose escalation. However, tolerability varies significantly between individuals.

Who Should Choose Wegovy?

Wegovy may be appropriate for:

  • Adults with obesity
  • Individuals who are overweight with weight-related health conditions
  • Patients primarily seeking significant weight reduction
  • People without diabetes who meet prescribing criteria

Who Should Choose Ozempic?

Ozempic may be suitable for:

  • Adults with type 2 diabetes
  • Patients requiring blood sugar control
  • Individuals who may also benefit from weight reduction
  • Patients with specific cardiovascular risk factors

Cost and Availability Considerations

Medication costs vary depending on dosage, healthcare provider fees, and treatment duration. Many patients researching ozempic singapore price, Semaglutide Singapore price, and prescription availability should understand that pricing can differ between providers and may change over time. Individuals searching for ozempic singapore where to buy, ozempic singapore clinic, or ozempic singapore online should only obtain prescription medications through licensed healthcare providers and regulated pharmacies. Purchasing medications from unverified sources increases the risk of counterfeit products and potential safety concerns.

Can You Switch Between Wegovy and Ozempic?

Some patients transition between medications due to treatment goals, availability, side effect management, or physician recommendations. Any switch should occur under medical supervision to ensure appropriate dosing and monitoring. A healthcare provider can determine whether transitioning between treatments is safe and appropriate for your circumstances.

Wegovy vs Ozempic Comparison Table

Feature Wegovy Ozempic
Active ingredient Semaglutide Semaglutide
Approved use Chronic weight management Type 2 diabetes management
Maximum weekly dose 2.4 mg 2.0 mg
Suitable for non-diabetics Yes Not the primary indication
HSA Singapore status Prescription-only medication Prescription-only medication
Average weight loss Approximately 14.9% in the STEP 1 trial when combined with lifestyle changes Generally lower and dose-dependent
Best suited for Individuals whose primary goal is weight loss Patients with type 2 diabetes who may also benefit from weight loss

Which Is Better for Different Goals?

Best for Weight Loss

Wegovy generally has an advantage for weight management because it is specifically designed and approved for that purpose.

Best for Type 2 Diabetes

Ozempic remains a strong option for patients who require blood sugar control while also benefiting from weight reduction.

Best Overall Choice

There is no single best medication for everyone. The most suitable option depends on your medical history, health goals, eligibility, and response to treatment.

Wegovy, in its turn, is not so widespread in the pharmacies of Singapore yet. Although it has been approved in a number of countries like the U.S and in some of the parts of Europe, its implementation within the Asian continent is still underway. This makes many people still maintain searches to get Ozempic that is more available.

Key Takeaways

  • Wegovy and Ozempic contain the same active ingredient, semaglutide.
  • Wegovy is specifically approved for chronic weight management, while Ozempic is approved for type 2 diabetes management.
  • Clinical studies show Wegovy may produce greater average weight loss because it is prescribed at a higher maintenance dose.
  • Both medications work best when combined with healthy eating habits and regular physical activity.
  • A doctor should assess your medical history, weight loss goals, and overall health before recommending treatment.

Can Lifestyle Changes Improve Results With Wegovy or Ozempic?

Both Wegovy and Ozempic work most effectively when combined with sustainable lifestyle changes. While these medications can help reduce hunger and support portion control, long-term success often depends on healthy eating habits, regular physical activity, adequate sleep, and stress management. Patients who follow a balanced nutrition plan and maintain consistent exercise routines typically achieve better weight loss outcomes than those relying on medication alone. Adopting healthy lifestyle habits can also help preserve muscle mass, improve metabolic health, and reduce the risk of weight regain after treatment.

How to Choose Between Wegovy and Ozempic in Singapore

Choosing between Wegovy and Ozempic depends on your health goals, medical history, and eligibility for treatment. Individuals primarily focused on significant weight reduction may benefit more from Wegovy, while those managing type 2 diabetes may find Ozempic a suitable option that also supports weight loss. Through DoctorOnCall Singapore, eligible patients can consult licensed doctors online, discuss suitable weight management options, and receive professional medical advice on whether Wegovy or Ozempic aligns with their treatment goals.

Why Do Wegovy and Ozempic Produce Different Weight Loss Results?

Although Wegovy and Ozempic contain the same active ingredient, semaglutide, they are prescribed at different maintenance doses and approved for different treatment goals. Wegovy reaches a higher maximum dose of 2.4 mg weekly, which can provide stronger appetite suppression and greater reductions in calorie intake. This is one of the main reasons clinical trials have shown greater average weight loss with Wegovy compared to Ozempic. However, treatment outcomes vary between individuals and depend on factors such as diet, physical activity, adherence to medication, and overall health status. A healthcare provider can help determine which option is more suitable based on your weight management goals and medical history.

Getting Professional Advice on Weight Loss Treatment

Although Wegovy and Ozempic contain the same active ingredient, semaglutide, they are prescribed at different maintenance doses and approved for different treatment goals. Wegovy reaches a higher maximum dose of 2.4 mg weekly, which can provide stronger appetite suppression and greater reductions in calorie intake. This is one of the main reasons clinical trials have shown greater average weight loss with Wegovy compared to Ozempic. However, treatment outcomes vary between individuals and depend on factors such as diet, physical activity, adherence to medication, and overall health status. A healthcare provider can help determine which option is more suitable based on your weight management goals and medical history.

What Should You Discuss With Your Doctor Before Starting Treatment?

Before starting Wegovy or Ozempic, it is important to have an open discussion with your doctor about your weight loss goals, medical history, current medications, and any existing health conditions. Certain factors, such as a history of pancreatitis, gallbladder disease, or endocrine disorders, may influence whether these medications are suitable for you. Your doctor can also explain what results to realistically expect, how to manage potential side effects, and the lifestyle changes that can support long-term success. Through DoctorOnCall Singapore, patients can access professional medical consultations and receive evidence-based recommendations tailored to their individual health needs.

The Importance of Long-Term Weight Management

Successful weight loss is not only about reaching a target number on the scale. Long-term weight management focuses on maintaining healthy habits that support lasting results and overall wellbeing. While medications such as Wegovy and Ozempic can help reduce appetite and support weight reduction, sustainable success often comes from combining treatment with balanced nutrition, regular physical activity, and ongoing medical guidance. Regular reviews with a healthcare professional can help track progress, address challenges early, and make adjustments when needed. Through DoctorOnCall Singapore, patients can receive continued support and personalised care to help them stay on track throughout their weight management journey.

Conclusion

If your primary goal is weight loss, Wegovy generally offers greater average weight reduction than Ozempic based on current clinical evidence. However, the right treatment depends on more than weight loss alone. Medical history, diabetes status, existing health conditions, treatment goals, and medication tolerance all play important roles in determining the most appropriate option. If you are considering semaglutide treatment for weight management, consult a licensed healthcare professional for personalised advice. Patients exploring ozempic singapore weight loss treatment options can speak with qualified doctors through DoctorOnCall Singapore to determine whether Wegovy, Ozempic, or another evidence-based treatment is suitable for their needs.

If you’re considering Ozempic or other weight loss treatments, it’s important to seek professional advice to ensure safe and effective results. Consult a licensed healthcare provider to determine whether Ozempic is suitable for your health goals and medical history. You can access licensed medical advice and conveniently obtain prescribed medications online through DoctorOnCall.

Book your Ozempic consultation with DoctorOnCall SG today — and take your first step toward safer, structured weight management.

Frequently Asked Questions

Is Wegovy more effective than Ozempic for weight loss?

Clinical evidence suggests Wegovy generally produces greater average weight loss because it is prescribed at a higher maintenance dose.

Ozempic is approved for type 2 diabetes management. Weight loss is a recognised effect of treatment, but approved indications may vary by region.

Yes. Wegovy was developed specifically for chronic weight management in eligible adults, including those without diabetes.

Some individuals may experience greater weight loss with Wegovy due to its higher dose, although individual results differ.

Both medications have similar side effect profiles because they contain semaglutide.

Wegovy’s availability in Singapore may differ from Ozempic’s. Consult a licensed doctor or check with a registered pharmacy for the most current information on availability and access.

Pricing varies by clinic, dosage, and treatment duration. DoctorOnCall SG doctors can provide a transparent cost breakdown during your consultation.

Yes. Licensed telemedicine providers like DoctorOnCall Singapore can assess your eligibility and issue a prescription through a regulated online consultation process.

The cost typically starts from a few hundred dollars per month depending on dosage. Subscription and bulk purchase discounts are available.

Yes. All orders are packaged securely and discreetly to protect your privacy.

Standard delivery takes 3–5 working days, with express shipping available.

Absolutely. We only provide original, pharmacy-dispensed Ozempic from licensed and regulated sources.

People Also Ask

Is Ozempic used for weight loss?

Ozempic is not recommended in weight loss. But semaglutide has been used in weight loss under the name Wegovy. Ozempic contains lower dose of semaglutide compared to Wegovy. It is worth mentioning that when you begin taking any of these drugs to lose weight, your body will get accustomed to it and create a new norm.

Ozempic is a prescription-only drug that is only legal in Singapore and has been most commonly used to treat diabetes type 2.

The most common side effects of Ozempic are nausea, vomiting, diarrhea, stomach pain, constipation, upset stomach, heartburn, burping, gas, bloating, loss of appetite, runny nose or sore throat, stomach flu symptoms or headache, dizziness, tiredness, and low blood sugar (in diabetics with type 2).

Ozempic raises the amount of incretins -hormones- produced by the stomach released when you eat. It is effective by enabling your body to create extra insulin when it is necessary. It also lowers the volume of glucose, or sugar, that the liver produces, and it slows down the rate of food digestion.

Ozempic Rx should not be used in case you or any members of your family had MTC before, or in case you have an endocrine system disorder known as Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

It has been indicated that Ozempic would aid an average weight loss of approximately 6kg in 40 weeks. But since this is an average, it is not known to what degree each person will lose weight on Ozempic.

Is Ozempic safe? Weight loss by using ozempic or other semaglutide is not safe. It is discouraged because it may cause (or contribute to) a number of eating disorders, such as anorexia nervosa and bulimia nervosa.

Will Ozempic or Wegovy fat belly? The answer appears to be yes. The same Novo Nordisk-funded randomized controlled trial of nearly 2,000 overweight or obese non-diabetic adults also reported their visceral or belly fat was less than at baseline with semaglutide, as was their total fat mass.

Semaglutide (Ozempic/Wegovy)

Semaglutide injections cost between Ss400 and Ss600 per pen in Singapore where an injection pen has four doses of semaglutide per week. The drug begins with 0.25mg per week during the initial month with a gradual rise in dosage to 1mg or 2.4mg depending on the response and tolerance.

The injector is a very thin needle that enters the drug right under the skin, therefore, it is not injected into the muscle or the vein. In your thigh, stomach or upper arm you will inject. This injection may be painful to some degree but otherwise, it is not painful to majority.

You must have a prescription of Ozempic, yes. Excessive use of Ozempic or even using it improperly may cause such conditions as low blood sugar or harm to your pancreas or kidney. Inappropriate dosage can also cause the side effects that are not so pleasant as nausea, vomiting or diarrhea.

Your Ozempic face can also disappear once you use GLP-1 medications when you gain back the weight that you have lost. Nonetheless, it may affect your general health and wellbeing in an adverse way.

Nausea is most of the time mild to moderate and at its worst when you are first starting on the drug or when you are raising its dosage. It should ease up over time. Ozempic side effects included almost 1 out of every 10 individuals in the clinical trial throwing up. This may be due to the decreased rate of digestion and additional pressure in the belly region it imposes.

Ozempic Face is the primary cause of the following symptoms: Skin on the jawline (jowls), cheeks and under the eyes are sagging.

1. Sunken cheeks.

2. Hollow eye area.

To a few patients, the use of Ozempic may cause pancreatitis, which is the inflammation of the pancreas. This is mentioned on the warnings to Ozempic and before prescribing the drug, doctors will usually screen a medical history of a patient to identify any increased risk of pancreatic issues.

Ozempic without insurance costs approximately 998 per month list price. The producer of Ozempic, Novo Nordisk, has a direct-to-consumer program which brings the price to $499 per month; this plan is only offered to self-patients.

Ozempic has weight loss applicants.

  • A BMI over 30, or.
  • BMI greater than 27, and at least one of these weight-related health issues (e.g., type 2 diabetes, PCOS, high blood pressure)

Both the alcohol and the Ozempic have the risk of pancreatitis and kidney damage. It might not be a huge problem with Ozempic to have a drink or two every now and then. However, when you use Ozempic in combination with long-term or heavy alcohol consumption, two serious complications can be more likely, namely, pancreatitis and kidney damage.

Hair loss is not directly caused by Ozempic, but the quick weight loss that can occur with this medication commonly results in telogen effluvium which is a temporary condition of excessive hair loss. This physical burden on the body, coupled with possible nutritional deficiencies due to the lack of appetite can also be a cause of the hair loss. It typically lasts and must end once the body returns to normalcy, however, it is advisable to visit a physician in case the ailment persists or when you feel that you are having nutritional deficiencies.

Yes Ozempic may also make some individuals feel tired or fatigued, but it was defined as a rare side effect in clinical trials. The effect is mostly temporary and is observed in the first weeks of treatment as the body adapts to the effect of the medication on the blood sugar and appetite. These may be caused by hormonal changes, lack of calories and blood glucose variation.

Studies indicate that Ozempic promotes weight reduction of approximately 1kg or approximately 1.1% body weight in one month. Two months later, it is approximately 2kg or 2.2 of body weight.

It is quite normal to gain weight once Ozempic is stopped, and most people regain as much as two thirds of their weight in the first year.

Injecting Ozempic into the body is best done at the front of the thighs, at the front of the waist (abdomen) or even upper arms. They advise you change the location of injection every time you inject. In 4 weeks, you should take an increase in dose to 0.5 mg one week unless otherwise advised by your doctor.

Ozempic begins to act 1-3 days following the injection. Ozempic can also take 4 to 8 weeks before you start to feel the benefit and you actually feel the full effect after you begin treatment. Once you have been doing well at the current dose of Ozempic with a minimum of 4 weeks, your doctor can adjust your dose up to 1mg.

Is Ozempic made of lizard-venom? No, it is not full of lizard venom. However, drugs such as Ozempic were invented due to the work of a species of lizard that is called the Gila monster and whose venom opened the door to these medications. The reason is that it has exendin-4, a peptide related to GLP-1 in humans.

Ozempic is able to interact with insulin. It is also a reaction to insulin releasing drugs like sulfonylureas and glinides. Hypoglycemia, or low blood glucose is more probable under this interaction.

In six weeks, Dr. Shah reports that you will begin noticing the action of the medicine-which may indicate that you do not feel as hungry as you usually are. However, once again, all people are different.

Doctors usually will not prescribe Ozempic to some individuals. This involves individuals whose personal or family history has some thyroid cancers. It also consists of individuals who are or were affected in multiple endocrine neoplasia syndrome type 2 (MEN2).

Research and clinical trials established that the Ozempic may also induce fatigue in about 11 percent of the patients.

Weight loss drugs based on semaglutide, such as Ozempic, Wegovy, Rybelsus, and others, are all prescription-only drugs in Singapore. You should be consulted in detail in order to evaluate your eligibility and to check your safety during the treatment course.

Since Ozempic is a prescription drug, you will have to discuss it with a licensed health provider to know whether you are eligible to receive this medicine. You may do that during a face-to-face appointment or occasionally through telehealth.

Ozempic ® has severe side effects, which include:

  • inflammation of your pancreas (pancreatitis).
  • changes in vision.
  • low blood sugar (hypoglycemia).
  • dehydration causing kidney issues.
  • severe stomach problems.
  • serious allergic reactions.
  • gallbladder problems.

It can be used to make your body produce more insulin and slow down your digestion. Although this may result in better blood sugar level and weight loss, it may also lead to gastrointestinal (GI) adverse effects, including nausea. The most frequent side effect of Ozempic is nausea.

When you are not losing weight on Ozempic or some other GLP-1 drugs, it could be due to your metabolism or calorie burning rate. It may be referred to as the Ozempic plateau, but that can occur in an event of any weight loss program.

Note that Ozempic can lead to mild nausea or constipation which usually passes after a few weeks. Gastrointestinal symptoms may temporarily get worse or appear in the first place upon increasing the dosage. You can modify your diet and take over-the-counter medication to discontinue discomfort and alleviate nausea or other symptoms.

First, semaglutide impacts the pancreas and causes it to secrete more insulin. The insulin is then absorbed into the blood, and decreases the blood sugar. Second, Ozempic blocks the excessive series of sugar release in the bloodstream of your liver temporarily. Lastly, the drug slows down your intestinal passage in your stomach.

Does Manulife cover Ozempic to lose weight? No, Manulife does not provide cover of Ozempic weight loss when this drug is used off-label. But in case of the prescription of Ozempic to treat Type 2 diabetes, it might be covered but only after prior approval.

Ozempic can be given to individuals with prediabetes as prescribed by some doctors, particularly those who are also determined to be obese (body-mass index of 30kg or above). It should be noted that off label use of Ozempic is off label, i.e. it is not approved by the FDA.

Although this term is not a clinical one, people are using it to refer to unexpected alterations in the size and shape of the breasts that a result of the rapid weight loss caused by GLP-1 medications. This condition can be accompanied by a loss of volume, sagging, tenderness, and in some instances, changes in the size of the breast e.g. swelling.

The fast loss of weight with the help of drugs such as Ozempic, Wegovy, or Mounjaro may be life-altering. But to other people, there is a less attractive side effect of this change, commonly known as Ozempic Butt. This condition is marked by flatness, loss of volume of the buttocks and sagging.

The majority of the patients lose 15 pounds of weight in 2-3 months of treatment.

Drugs such as Ozempic and Wegovy have provided weight loss to millions of individuals who never expected to get such results. However, when you are feeling a bit emotionally different (irritated, nervous or depressed than usual), do not shrug it off. These GLP-1 side effects are beginning to be proving to be more than just physical.

The most common side effect of Ozempic is nausea. Still, not everyone has it. In the clinical trial approximately 1 out of 5 individuals had it. Nausea is typically mild to moderate and worst of all when you first begin the medication or when you are raising the dosage.

Consequently, when taking Ozempic, the following facial changes can be observed: more aging with lines and wrinkles, loss of fat which is considered to make skin loose and saggy, and hollow.

Ozempic is a glucagon-like peptide-1 receptor agonist (GLP-1RA) that retards the rate of stomach emptying. It can be characterized by the mild to moderate stomach upset and nausea. These are symptoms which may be short-lived and temporary. To alleviate the symptoms of indigestion, consume less food in parts over the day.

The maximum time that one can safely take Ozempic is unknown, provided one tolerates it and the doctor recommends it. The duration of most of the trials regarding medicines in this class of drugs covers a period of up to 18 months.

  • S$400 to S$600 per pen
  • Semaglutide (Ozempic/Wegovy)

In Singapore Semaglutide injection costs between S$400 and S600 per pen with 4 weekly doses per pen. The drug begins with 0.25mg per week in the first month, and then moves slowly to 1mg or 2.4 mg depending on the individual response and tolerability.

No, Ozempic is not safe or approved weight loss since it is only FDA approved in type 2 diabetes. Although it has weight-loss as a side effect, its use as such is off-label, and potentially risky, with serious side effects, drug interactions, and shortages posing a risk to people with diabetes. The same active ingredient, semaglutide, is also available as an approved weight loss under the name Wegovy.

Who should not use Ozempic?

  • Allergies to Ingredients. Ozempic should not be used in people who are allergic to one of the following.
  • Thyroid Cancer or Endocrine condition. …
  • Slowed Stomach Emptying. …
  • Kidney Problems. …
  • Vision Problems. …
  • Low Blood Sugar (Hypoglycemia). …
  • Other Medicines and Supplements. …
  • Pregnancy.

Without insurance or paying on your own, you may receive Ozempic 499 a month in 2 ways. Ozempic® with NovoCare® Pharmacy allows having it delivered to your home. You are also entitled to one of these savings offers which you can pick up at the local pharmacy when you collect your prescription.

These are five foods and beverages that should be avoided when using Ozempic.

  • Foods that are high in fat. High-fat foods may increase the side effects of Ozempic.
  • Sugary foods and drinks. Well, you are a diabetic; you understand that you have to restrict the amount of sweets and drinks.
  • Ultra-processed carbohydrates. …
  • Starchy vegetables. …
  • Alcohol.

Yes, Ozempic may make one feel tired or fatigued, but it is an uncommon side effect in clinical trials. Such an effect normally subsides after the first few weeks of medication as the body gets used to the actions of the medication on blood sugar and appetite. The possible reasons are hormonal changes, low calorie consumption and variations in the levels of blood glucose.